Cognitivedysfunction相关论文
目的:分析血清α-突触核蛋白(α-syn)、微小核糖核酸-214(miR-214)联合检测在帕金森病(PD)患者认知功能障碍评估中的应用价值。方......
认知功能障碍严重影响患者生活质量,临床上常见于脑缺血疾病、脓毒症及术后等,其病因包括脑内调节分子表达异常、脑组织缺血性损伤及......
目的 分析老年血管性痴呆(VD)患者认知功能障碍实施康复护理的临床效果.方法 将60例老年VD患者作为本次研究对象,均来源于我院2020......
目的:评价长期摄入ω-3多不饱和脂肪酸(ω-3 PUFAs)对术后认知功能障碍(POCD)小鼠海马小胶质细胞活化的影响。方法:清洁级健康雄性......
认知功能障碍与神经细胞凋亡、自噬、氧化应激及神经炎症等多方面有着密切的联系。在许多临床疾病或刺激因素的作用下,患者会出现认......
目的:探讨脑小血管病(CSVD)患者应用远隔缺血预适应(RIPC)治疗对其认知功能障碍的影响。方法:抽取2021年1月至2021年9月赤峰市医院......
目的:探讨正念疗法对老年糖尿病伴认知功能障碍患者血糖控制水平及生活质量的影响。方法:选取新乡市第一人民医院2018年8月至2020......
目的:明确心房颤动患者认知功能障碍的危险因素,并构建风险预测模型,为改善患者认知功能提供数据支持。方法:采用便利抽样法对2020年......
目的 无创低成本虚拟现实技术对于轻度认知障碍患者的早期评估和认知干预具有重要意义.本研究旨在通过文献计量学分析,展示虚拟现......
DNA vaccines targeting amyloid-β oligomer ameliorate cognitive deficits of aged APP/PS1/tau triple-t
The amyloid-β (Aβ) oligomer, rather than the Aβ monomer, is considered to be the primary initiator of Alzheimer\'s ......
目的:分析脑卒中后认知功能障碍患者居家照顾者感受负担与疾病获益感,为制订针对性的干预对策提供参考。方法:采用立意抽样法,选择20......
Background::Microglia plays an indispensable role in the pathological process of sleep deprivation (SD). Here, the poten......
目的 分析认知障碍脑瘫患儿行护理干预的临床价值?方法 纳入我院于2018年10月至2019年10月收治的脑瘫伴认知障碍患儿34例,根据入组......
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The expanded lifespan of people, while a positive advance, has also amplified the prevalence of age-related disorders, w......
Developments in Biological Mechanisms and Treatments for Negative Symptoms and Cognitive Dysfunction
The causal mechanisms and treatment for the negative symptoms and cognitive dysfunction in schizophrenia are the main is......
Occupational exposure to 1-bromopropane (1-BP) induces learning and memory deficits.However,no therapeutic strategies ar......
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Abnormal degree centrality of functional hubs in male patients with obstructive sleep apnea:evidence
Purpose Obstructive sleep apnea (OSA) has been associated with changes in brain structure and local function in certain ......
Obstructive sleep apnea syndrome (OSAS) is characterized by chronic nocturnal intermittent hypoxia and sleep fragmentati......
The effect of statins for delirium and subsequent cognitive impairment in patients with critical ill
目的 Studies demonstrate the benefit of statins to prevent short-term delirium and long-term cognitive dysfunction,howev......
Aim: Hyperphosphorylation of tau mediated by mTOR/p70S6K pathway has been thought to contribute to cognitive dysfunction......
Type 2 diabetes increase the risk of development of cognitive dysfunction in the elderly, in the form of shortterm memor......
Berberine improves cognitive impairment and ameliorates tau hyperphosphorylation by limiting the sel
Background: Berberine(BBR)plays an important role in the prevention and treatment of Alzheimers disease(AD).The present ......
Background: Berberine(BBR)has neuroprotective effects on a variety of brain diseases,including Alzheimers disease(AD).Th......
Correlation between Cognitive Function and The Hippocampal Atrophy and Brain White Matter lesions in
Objectives To observe the change of the cognitive function,hippocampus and brain white matter in subjects with obstructi......
目的:评价海马β淀粉样蛋白42(Aβn 42)沉积诱发中性粒细胞聚集在七氟烷麻醉导致老龄大鼠血脑屏障损伤中的作用。n 方法:......
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Effect of Rapid Eye Movement Sleep Behavior Disorder on Obstructive Sleep Apnea Severity and Cogniti
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卡西酮类策划药的结构和药效与苯丙胺类兴奋剂相似,多通过对已管制毒品进行细微化学修饰或全新设计、筛选获得,使人体产生类似或更强......
目的探讨老年椎管内麻醉患者术中脑氧饱和度对早期术后认知功能障碍(POCD)的影响。方法选择2019年7-10月包头医学院第一附属医院60岁......
Artemisinin improves neurocognitive deficits associated with sepsis by activating the AMPK axis in m
Sepsis is life-threatening organ dysfunction due to dysregulated systemic inflammatory and immune response to infection,......
小细胞肺癌(SCLC)是肺癌中恶性程度较高的病理类型,早期易发生脑转移。预防性全脑照射(PCI)可以降低SCLC患者脑转移的风险,但PCI导致......
目的评价非心脏手术老年患者术前衰弱与术后认知功能障碍(POCD)的关系。方法择期全麻下行非心脏手术老年患者336例,年龄≥65岁,性别......
目的探究叙事治疗对职业性急性化学物中毒性脑病恢复期患者的认知、情绪以及治疗满意度的影响。方法于2019年6至7月,将60例职业性化......
血管性认知障碍(vascular cognitive impairment)是常见认知障碍类型,目前尚无针对性的治疗方案,尤其进展至中重度痴呆期。本文围绕着......
目的探讨米诺环素对七氟烷麻醉诱导老龄小鼠认知障碍的改善作用及其机制。方法清洁级C57BL/6小鼠75只按照随机数字表法分为对照组(......
目的:观察电针及加减通窍活血汤联合胞磷胆碱综合治疗轻度脑损伤后认知功能障碍的疗效。方法:选入符合标准的轻度认知功能障碍的患者......
Long-term adenosine A1 receptor activation-induced sortilin expression promotes α-synuclein upregula
Prolonged activation of adenosine A1 receptor likely leads to damage of dopaminergic neurons and subsequent development ......
目的探讨抑郁症患者认知功能障碍的特征及其与血清脑源性神经营养因子(BDNF)水平的关系。方法采用北京版蒙特利尔认知评估量表(MoC......
目的探讨细胞外信号调节激酶2(ERK2)及神经细胞黏附分子1(NCAM1)在癫痫认知功能障碍中的作用及抗痫、促智药物对二者作用。方法将1......
目的探讨脑源性神经营养因子(BDNF)基因与抑郁症患者认知功能障碍的关系。方法采用北京版蒙特利尔认知评估量表(MoCA-BJ)分别对73......
目的探讨虾青素与氯化锂治疗慢性有机磷中毒小鼠认知障碍的协同作用。方法成年健康雄性昆明小鼠55只,采用随机数字法选8只作为对照......
目的 探讨慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)患者血浆中性粒细胞明胶酶蛋白(neutrophil gelatinase-......
认知功能障碍作为慢性疲劳综合征(CFS)、纤维肌肉痛(FM)患者普遍存在的临床症状,其发生的神经机制尚不明确。事件相关电位(ERP)可实......
目的探讨重度抑郁症患者外周血差异表达的circRNA与认知功能的关系。方法首先分别选取5例抑郁症患者和健康人进行基因芯片筛查,确定......
目的探讨煤炭企业工人认知功能的影响因素。方法对某煤炭企业3 205例工人进行健康检查,检查内容包括身高、体质量、血压、血常规、......
Kai Xin San (KXS, containing ginseng, hoelen, polygala, and acorus), a traditional Chinese herbal compound, has been fou......